VEGF-A/NRP1 STIMULATES GIPC1 AND SYX COMPLEX FORMATION TO PROMOTE RHOA ACTIVATION AND PROLIFERATION IN SKIN CANCER CELLS

VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells

Neuropilin-1 (NRP1) has been identified as a VEGF-A receptor.DJM-1, a human skin cancer cell line, expresses endogenous VEGF-A and NRP1.In the present study, the RNA interference of VEGF-A or NRP1 suppressed DJM-1 cell proliferation.Furthermore, the overexpression of the NRP1 wild type restored shNRP1-treated DJM-1 cell proliferation, whereas NRP1

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Is it time to scrap Scadding and adopt computed tomography for initial evaluation of sarcoidosis? [version 1; referees: 2 approved]

In this review, we argue for the use of high-resolution computed tomography (HRCT) over chest X-ray in the initial evaluation of patients with sarcoidosis.Chest X-ray, which has long been used to classify disease severity MAG PWD RAS LEM and offer prognostication in sarcoidosis, has clear limitations compared with HRCT, including wider interobserve

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A Novel Image Encryption Scheme Based on Collatz Conjecture

Image encryption methods aim to protect content privacy.Typically, they encompass 5 Piece Modular Sectional scrambling and diffusion.Every pixel of the image is permuted (scrambling) and its value is transformed according to a key (diffusion).Although several methods have been proposed in the literature, some of them have been cryptanalyzed.In this

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